Notícias

LBMCF

Pesquisadora do LBMCF visita Ragon Institute

No mês de julho de 2018 a pesquisadora e aluna de doutorado da Universidade Federal de Minas Gerais (UFMG) MSc. Paula Luize Camargos Fonseca integrante do Laboratório de Biologia Molecular e Computacional de Fungos (LBMCF) realizou uma visita técnica ao Ragon Institute na Cidade de Cambridge, Massachusetts, EUA, sob a supervisão do médico e pesquisador Wilfredo Beltran com a missão de ampliar  a rede de colaboração do nosso grupo de pesquisa. Durante a visita, Paula aprendeu sobre técnicas de microscopia eletrônica, biologia molecular, proteômica e biossegurança.

O Reagon Institute foi criado em 2009 em uma colaboração entre o Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT) e Harvard University. O instituto desenvolve pesquisas nas áreas de virologia e imunologia, especificamente a fim de contribuir para os estudos do HIV e para a descoberta de uma vacina para combater o vírus.

 

SAIBA mais SOBRE  O RAGON INSTITUTE

Notícias

ARTIGO

Comparative mangrove metagenome reveals global prevalence of heavy metals and antibiotic resistome across different ecosystems

The mangrove ecosystem harbors a complex microbial community that plays crucial role in biogeochemical cycles. In this study, we analyzed mangrove sediments from India using de novo whole metagenome next generation sequencing (NGS) and compared their taxonomic and functional community structures to mangrove metagenomics samples from Brazil and Saudi Arabia. The most abundant phyla in the mangroves of all three countries was Proteobacteria, followed by Firmicutes and Bacteroidetes. A total of 1,942 genes were found to be common across all the mangrove sediments from each of the three countries. The mangrove resistome consistently showed high resistance to fluoroquinolone and acriflavine. A comparative study of the mangrove resistome with other ecosystems shows a higher frequency of heavy metal resistance in mangrove and terrestrial samples. Ocean samples had a higher abundance of drug resistance genes with fluoroquinolone and methicillin resistance genes being as high as 28.178% ±3.619 and 10.776% ± 1.823. Genes involved in cobalt-zinc-cadmium resistance were higher in the mangrove (23.495% ±4 .701) and terrestrial (27.479% ± 4.605) ecosystems. Our comparative analysis of samples collected from a variety of habitats shows that genes involved in resistance to both heavy metals and antibiotics are ubiquitous, irrespective of the ecosystem examined.

 

 

Laboratório de biologia molecular e computacional de fungos

Laboratório de Biologia Molecular e Computacional de Fungos (LBMCF) (Sala 158, Bloco J4, 4º  andar)

Gabinete Professor Dr. Aristóteles Góes Neto (Coordenador LBMCF) (Sala 53, Bloco J3, 3º  andar)

Universidade Federal de Minas Gerais (UFMG), Instituto de Ciências Biológicas (ICB), Departamento de Microbiologia (DMic)

 E-mails: arigoesneto@icb.ufmg.br / arigoesneto@pq.cnpq.br / arigoesneto@gmail.com | Telefone: +55 31 3409-3050

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