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LBMCF

PhD student of LBMCF visits Ragon Institute

In July 2018, the graduate researcher and phD student at the Federal University of Minas Gerais (UFMG) Msc. Paula Luize Camargos Fonseca, member of the Laboratory of Computational and Molecular Biology of Fungi (LBMCF) made a tecnical visit to the Ragon Institute, in Cambridge, MA, under supervision of the doctor and researcher Wilfredo Beltran, with the mission of increasing the colaboration newtwork of our research group. During this visit, Paula learned about techniques of electronic microscopy, molecular biology, proteomics and biosafety. The Regon Institute was created in 2009 in a collaboration between  Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT) and Harvard University. The institute develops research in virology and immunology, specifically to contribute to HIV studies and to the development of a vaccine to cure the virus.

 

 

 

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ARTICLE

Comparative mangrove metagenome reveals global prevalence of heavy metals and antibiotic resistome across different ecosystems

The mangrove ecosystem harbors a complex microbial community that plays crucial role in biogeochemical cycles. In this study, we analyzed mangrove sediments from India using de novo whole metagenome next generation sequencing (NGS) and compared their taxonomic and functional community structures to mangrove metagenomics samples from Brazil and Saudi Arabia. The most abundant phyla in the mangroves of all three countries was Proteobacteria, followed by Firmicutes and Bacteroidetes. A total of 1,942 genes were found to be common across all the mangrove sediments from each of the three countries. The mangrove resistome consistently showed high resistance to fluoroquinolone and acriflavine. A comparative study of the mangrove resistome with other ecosystems shows a higher frequency of heavy metal resistance in mangrove and terrestrial samples. Ocean samples had a higher abundance of drug resistance genes with fluoroquinolone and methicillin resistance genes being as high as 28.178% ±3.619 and 10.776% ± 1.823. Genes involved in cobalt-zinc-cadmium resistance were higher in the mangrove (23.495% ±4 .701) and terrestrial (27.479% ± 4.605) ecosystems. Our comparative analysis of samples collected from a variety of habitats shows that genes involved in resistance to both heavy metals and antibiotics are ubiquitous, irrespective of the ecosystem examined.

 

 

Molecular and Computational Biology of Fungi Lab

Laboratório de Biologia Molecular e Computacional de Fungos (LBMCF) (Sala 158, Bloco J4, 4º  andar)

Gabinete Professor Dr. Aristóteles Góes Neto (Coordenador LBMCF) (Sala 53, Bloco J3, 3º  andar)

Universidade Federal de Minas Gerais (UFMG), Instituto de Ciências Biológicas (ICB), Departamento de Microbiologia (DMic)

 E-mails: arigoesneto@icb.ufmg.br / arigoesneto@pq.cnpq.br / arigoesneto@gmail.com | Telefone: +55 31 3409-3050

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