http://lattes.cnpq.br/5903380321308935
Áreas de pesquisa: Imunologia das doenças parasitárias, infecciosas e metabólicas
Produtos, Patentes e Publicações relevantes:
Medeiros NI, Gomes JAS, Fiuza JA, Sousa GR, Almeida EF, Novaes RO, Rocha VLS, Chaves AT,
Dutra WO, Rocha MOC, Correa-Oliveira R. MMP-2 and MMP-9 plasma levels are potential
biomarkers for indeterminate and cardiac clinical forms progression in chronic Chagas
disease. Sci Rep. 2019 Oct 2;9(1):14170. doi: 10.1038/s41598-019-50791-z.
Sousa GR, Gomes JA, Fares RC, Damásio MP, Chaves AT, Ferreira KS, Nunes MC, Medeiros NI,
Valente VA, Corrêa-Oliveira R, Rocha MO.Plasma cytokine expression is associated with
cardiac morbidity in chagas disease. PLoS One. 2014 Mar 6;9(3):e87082. doi:
10.1371/journal.pone.0087082. eCollection 2014.
Cassirer-Costa F, Medeiros NI, Chaves AT, Lyon S, Coelho-Dos-Reis JGA, Ribeiro-Junior AF,
Correa-Oliveira R, Rocha MOC, Gomes JAS. Cytokines as biomarkers to monitoring the
impact of multidrug therapy in immune response of leprosy patients. Cytokine. 2017
Sep;97:42-48. doi: 10.1016/j.cyto.2017.05.020. Epub 2017 May 29.
Mattos RT, Medeiros NI, Menezes CA, Fares RC, Franco EP, Dutra WO, Rios-Santos F, Correa-
Oliveira R, Gomes JA. Chronic Low-Grade Inflammation in Childhood Obesity Is Associated
with Decreased IL-10 Expression by Monocyte Subsets. PLoS One. 2016 Dec
15;11(12):e0168610. doi: 10.1371/journal.pone.0168610. eCollection 2016.
Medeiros NI, Mattos RT, Menezes CA, Fares RCG, Talvani A, Dutra WO, Rios-Santos F, Correa-
Oliveira R, Gomes JAS. IL-10 and TGF-β unbalanced levels in neutrophils contribute to
increase inflammatory cytokine expression in childhood obesity. Eur J Nutr. 2018
Oct;57(7):2421-2430. doi: 10.1007/s00394-017-1515-y. Epub 2017 Jul 22.
de Araújo FF, Corrêa-Oliveira R, Rocha MO, Chaves AT, Fiuza JA, Fares RC, Ferreira KS, Nunes
MC, Keesen TS, Damasio MP, Teixeira-Carvalho A, Gomes JA Foxp3+CD25(high) CD4+
regulatory T cells from indeterminate patients with Chagas disease can suppress the effector
cells and cytokines and reveal altered correlations with disease severity.Immunobiology.
2012 Aug;217(8):768-77. doi: 10.1016/j.imbio.2012.04.008. Epub 2012 May 9.
Gomes JA, Campi-Azevedo AC, Teixeira-Carvalho A, Silveira-Lemos D, Vitelli-Avelar D,
Sathler-Avelar R, Peruhype-Magalhães V, Silvestre KF, Batista MA, Schachnik NC, Correa-
Oliveira R, Eloi-Santos S, Martins-Filho OA.
Impaired phagocytic capacity driven by downregulation of major phagocytosis-related cell
surface molecules elicits an overall modulatory cytokine profile in neutrophils and
monocytes from the indeterminate clinical form of Chagas disease. Immunobiology. 2012
Oct;217(10):1005-16. doi: 10.1016/j.imbio.2012.01.014. Epub 2012 Jan 20.
Gomes JA, Bahia-Oliveira LM, Rocha MO, Busek SC, Teixeira MM, Silva JS, Correa-Oliveira R.
Type 1 chemokine receptor expression in Chagas' disease correlates with morbidity in
cardiac patients. Infect Immun. 2005 Dec;73(12):7960-6.
Gomes JA, Bahia-Oliveira LM, Rocha MO, Martins-Filho OA, Gazzinelli G, Correa-Oliveira R.
Evidence that development of severe cardiomyopathy in human Chagas' disease is due to a
Th1-specific immune response. Infect Immun. 2003 Mar;71(3):1185-93.
E-mails: juliana@icb.ufmg.br; jacis@icb.ufmg.br