Carvalho, T.G.; Alves-Silva, J. ; De Souza, J.M. ; Real, A.L.C.V. ; Doria, J.G. ; Vieira, E.L.M. ; Gomes, G.F. ; De Oliveira, A.C. ; Miranda, A.S. ; Ribeiro, F.M. . Metabotropic glutamate receptor 5 ablation accelerates age-related neurodegeneration and neuroinflammation. Neurochemistry International, v. 126, p. 218-228, 2019.
PUBMED
Miranda, A.S.; Cardozo, P.L. ; Silva, F.R. ; De Souza, J.M. ; Olmo, I.G. ; Cruz, J.S. ; Gomez, M.V. ; Ribeiro, F.M. ; Vieira, L.B. . Alterations of Calcium Channels in a Mouse Model of Huntington’s Disease and Neuroprotection by Blockage of CaV1 Channels. ASN Neuro, v. 11, p. 175909141985681, 2019.
PUBMED
Jackman J. A., Costa V. V., Park S., Real A. L. C. V., Park J. H., Cardozo P. L., Ferhan A. R., Olmo I. G., Moreira T. P., Bambirra J. L., Queiroz V. F., Queiroz-Junior C. M., Foureaux G., Souza D. G., Ribeiro F. M., Yoon B. K., Wynendaele E., Spiegeleer B. D., Teixeira M. M. and Cho N.-J. (2018). Therapeutic treatment of Zika virus infection using a brain-penetrating antiviral peptide. Nature Materials, 17 971-977.
PUBMED
Olmo I. G., Carvalho T. G., Costa V. V., Alves-Silva J., Ferrari C. Z., Izidoro-Toledo T. C., Silva J. F., Teixeira A. L., Souza D. G., Marques J. T., Teixeira M. M., Vieira L. B., and Ribeiro F. M. (2017) Zika Virus Promotes Neuronal Cell Death in a Non-cell Autonomous Manner by Triggering the Release of Neurotoxic Factors. Frontiers in Immunology, in press.
PUBMED
Costa V. V., del Sarto J. L., Rocha R. F., Silva F. R., Doria J. G., Olmo I. G., Marques R. E., Queiroz-Junior C. M., Foureaux G., Araujo J. M. S., Cramer A., Real A. L. C. V., Ribeiro L. S., Sardi S. I., Ferreira A. J., Machado F. S., de Oliveira A. C. P., Teixeira A. L., Nakaya H. I., Souza D. G., Ribeiro F. M.*, and Teixeira M. M.* (2017) N -Methyl-d-Aspartate (NMDA) Receptor Blockade Prevents Neuronal Death Induced by Zika Virus Infection. mBio, 8, e00350-17.
PUBMED
Silva F. R., Miranda A. S., Santos R. P. M., Olmo I. G., Zamponi G. W., Dobransky T., Cruz J. S., Vieira L. B., and Ribeiro F. M. (2017) N-type Ca 2+ channels are affected by full-length mutant huntingtin expression in a mouse model of Huntington’s disease. Neurobiology of Aging, 55, 1-10.
PUBMED
Batista E. M. L., Doria J. G., Ferreira-Vieira T. H., Alves-Silva J., Ferguson S. S. G., Moreira F. A., and Ribeiro F. M. (2016) Orchestrated activation of mGluR5 and CB1 promotes neuroprotection. Molecular Brain, 9, 80.
PUBMED
Doria J. G., de Souza J. M., Andrade J. N., Rodrigues H. A., Guimaraes I. M., Carvalho T. G., Guatimosim C., Dobransky T., and Ribeiro F. M. (2015) The mGluR5 positive allosteric modulator, CDPPB, ameliorates pathology and phenotypic signs of a mouse model of Huntington’s disease. Neurobiology of Disease, 73, 163-173.
PUBMED
Ribeiro F. M., Devries R. A., Hamilton A., Guimaraes I. M., Cregan S. P., Pires R. G. W., and Ferguson S. S. G. (2013) Metabotropic glutamate receptor 5 knockout promotes motor and biochemical alterations in a mouse model of huntington’s disease. Human Molecular Genetics, 23, 2030-2042.
PUBMED
Doria J. G., Silva F. R., Souza J. M., Vieira L. B., Reis H. J., Dobransky T., and Ribeiro F. M. (2013) Metabotropic glutamate receptor 5 positive allosteric modulators are neuroprotective in a mouse model of Huntington’s disease.British Journal of Pharm., 169, 909-921.
PUBMED
Ribeiro F. M., Paquet M., Ferreira L. T., Cregan T., Cregan S., and Ferguson S. S. G. (2010) Metabotropic glutamate receptor-mediated cell signaling pathways are altered in a mouse model of Huntington’s disease. J. Neuroscience, 30, 316-24.
PUBMED
Ribeiro F. M., Ferreira L. T., Paquet M., Cregan T., Ding Q., Gros R., and Ferguson S. S. G. (2009) Phosphorylation-independent regulation of metabotropic glutamate receptor 5 desensitization and internalization by G protein-coupled receptor kinase 2 in neurons. J. Biol. Chem., 284, 23444-53.
PUBMED
Ribeiro F. M., Alves-Silva J., Volknandt W., Martins-Silva C., Mahmud H., Wilhelm A., Gomez M. V., Rylett R. J., Ferguson S. S. G., Prado V. F., and Prado M. A. (2003) The hemicholinium-3 sensitive high affinity choline transporter is internalized by clathrin-mediated endocytosis and is present in endosomes and synaptic vesicles.J. Neurochem. 87, 136-146.
PUBMED