{"id":458,"date":"2023-11-03T13:12:13","date_gmt":"2023-11-03T16:12:13","guid":{"rendered":"https:\/\/neurobioquimica-com.umbler.net\/?page_id=458"},"modified":"2024-04-24T20:23:54","modified_gmt":"2024-04-24T23:23:54","slug":"publicacoes","status":"publish","type":"page","link":"https:\/\/sites.icb.ufmg.br\/neurobioquimica\/publicacoes\/","title":{"rendered":"Publica\u00e7\u00f5es"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"458\" class=\"elementor elementor-458\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-62ae033 e-flex e-con-boxed e-con e-parent\" data-id=\"62ae033\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-52903ad elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"52903ad\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;,&quot;_animation_delay&quot;:100}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Principais Publica\u00e7\u00f5es<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-98a98b1 e-flex e-con-boxed e-con e-parent\" data-id=\"98a98b1\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3c9d70b elementor-widget elementor-widget-spacer\" data-id=\"3c9d70b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-442a7d0 animated-slow e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"442a7d0\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;animation_delay&quot;:300}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-d215d4c e-con-full e-flex e-con e-child\" data-id=\"d215d4c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bbe1752 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"bbe1752\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul>\n<li><span style=\"font-weight: 400;\">de Souza J. M., Ferreira-Vieira T. H., Maciel E. M. A., Silva N. C., Lima I. B. Q., Doria J. G., Olmo I. G., <\/span><span style=\"font-weight: 400;\"><u>Ribeiro F. M.<\/u><\/span><span style=\"font-weight: 400;\"> (2022) <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35643779\/\"><span style=\"font-weight: 400; color: black;\">mGluR5 ablation leads to age-related synaptic plasticity impairments and does not improve Huntington&#8217;s disease phenotype.<\/span><\/a> <i><span style=\"font-weight: 400;\">Scientific Reports<\/span><\/i><span style=\"font-weight: 400;\">, <\/span><b>12<\/b><span style=\"font-weight: 400;\">, 8982. <\/span><\/li>\n<\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-bb27b45 e-con-full e-flex e-con e-child\" data-id=\"bb27b45\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6bc5920 elementor-widget elementor-widget-button\" data-id=\"6bc5920\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/doi.org\/10.1038\/s41598-022-13029-z\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">PUBMED<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6236401 animated-slow e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"6236401\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;animation_delay&quot;:300}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-2ae3302 e-con-full e-flex e-con e-child\" data-id=\"2ae3302\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5f93602 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"5f93602\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li><span style=\"font-weight: 400;\">Andrade T. A., Fahel J. S., de Souza J. M., Terra A. C., Souza D. G., Costa V. V., Teixeira M. M., Bloise E., <\/span><span style=\"font-weight: 400;\"><u>Ribeiro F. M.<\/u><\/span><span style=\"font-weight: 400;\"> (2022) Exposure to Zika Virus Results in sex-Specific Memory Deficits and Neurological Alterations in Adult Mice. <\/span><i><span style=\"font-weight: 400;\">ASN Neuro<\/span><\/i><span style=\"font-weight: 400;\">, <\/span><b>14<\/b><span style=\"font-weight: 400;\">, 175909142211212. <\/span><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1d8796d e-con-full e-flex e-con e-child\" data-id=\"1d8796d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9facd1b elementor-widget elementor-widget-button\" data-id=\"9facd1b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/doi.org\/10.1177\/17590914221121257\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">PUBMED<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-977145d animated-slow e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"977145d\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;animation_delay&quot;:300}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-898cfc8 e-con-full e-flex e-con e-child\" data-id=\"898cfc8\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c53e29b elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"c53e29b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li><span style=\"font-weight: 400;\">Olmo I. G., Olmo R.P., Gon\u00e7alves A. N. A., Pires R. G. W., Marques J. T., <\/span><span style=\"font-weight: 400;\"><u>Ribeiro F. M.<\/u><\/span><span style=\"font-weight: 400;\"> (2021) High-Throughput Sequencing of BACHD Mice Reveals Upregulation of Neuroprotective miRNAs at the Pre-Symptomatic Stage of Huntington\u2019s Disease. <\/span><i><span style=\"font-weight: 400;\">ASN Neuro<\/span><\/i><span style=\"font-weight: 400;\">, <\/span><b>13<\/b><span style=\"font-weight: 400;\">, 175909142110098. <\/span><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6d745a4 e-con-full e-flex e-con e-child\" data-id=\"6d745a4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f49868b elementor-widget elementor-widget-button\" data-id=\"f49868b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/doi.org\/10.1177\/17590914211009857\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">PUBMED<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c69085a animated-slow e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"c69085a\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;animation_delay&quot;:300}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-740203a e-con-full e-flex e-con e-child\" data-id=\"740203a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-30038f0 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"30038f0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li><span style=\"font-weight: 400;\">Jackman J. A., Costa V., Park S., Real A. L. C. V., Park J. H., Cardozo P. L., Ferhan A. R., Olmo I. G., Moreira T. P., Bambirra J., Queiroz V. F., Queiroz-Junior C. M., Foureaux G., Souza D. G., <\/span><span style=\"font-weight: 400;\"><u>Ribeiro F. M.<\/u><\/span><span style=\"font-weight: 400;\">, Yoon B. K., Wynendaele E., de Spiegeleer B., Teixeira M. M., and Cho N. (2018) Therapeutic Treatment of Zika Virus Infection Using a Brain-Penetrating 2 Antiviral Peptide. <\/span><i><span style=\"font-weight: 400;\">Nature Materials<\/span><\/i><span style=\"font-weight: 400;\">, <\/span><b>17<\/b><span style=\"font-weight: 400;\">,\u00a0971\u2013977<\/span><span style=\"font-weight: 400;\">.<\/span><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c0f97f0 e-con-full e-flex e-con e-child\" data-id=\"c0f97f0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ee3d363 elementor-widget elementor-widget-button\" data-id=\"ee3d363\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/doi.org\/10.1038\/s41563-018-0194-2\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">PUBMED<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-15d9d84 animated-slow e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"15d9d84\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;animation_delay&quot;:300}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-87b07a4 e-con-full e-flex e-con e-child\" data-id=\"87b07a4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ccb302b elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"ccb302b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul>\n \t<li><a href=\"http:\/\/lattes.cnpq.br\/3010280132812544\"><span style=\"font-weight: 400; color: black\">Doria J. G.<\/span><\/a><span style=\"font-weight: 400;\">, de Souza J. M.,\u00a0<\/span><a href=\"http:\/\/lattes.cnpq.br\/7568012626967603\"><span style=\"font-weight: 400; color: black\">Silva<\/span><\/a><span style=\"font-weight: 400;\"> F. R.,\u00a0Olmo I. G., Carvalho T. G.,\u00a0Alves-Silva J., Ferreira-Vieira T. H., Santos J. T., Xavier C. Q. S., Silva N. C., Maciel E. M. A., Conn P. J. and <\/span><span style=\"font-weight: 400;\"><u>Ribeiro F. M.<\/u><\/span><span style=\"font-weight: 400;\"> (2018) The mGluR5 positive allosteric modulator VU0409551 improves synaptic plasticity and memory of a mouse model of Huntington&#8217;s disease. <\/span><i><span style=\"font-weight: 400;\">J. Neurochem.<\/span><\/i><span style=\"font-weight: 400;\">, <\/span><b>147<\/b><span style=\"font-weight: 400;\">, 222-239<\/span><span style=\"font-weight: 400;\">.\u00a0 <\/span><\/li>\n<\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3a17fee e-con-full e-flex e-con e-child\" data-id=\"3a17fee\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f228720 elementor-widget elementor-widget-button\" data-id=\"f228720\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/doi.org\/10.1111\/jnc.14555\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">PUBMED<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-527e669 animated-slow e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"527e669\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;animation_delay&quot;:300}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-84d2740 e-con-full e-flex e-con e-child\" data-id=\"84d2740\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-cf7a483 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"cf7a483\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li><span style=\"font-weight: 400;\">Olmo I. G., Carvalho T. G., Costa V. V., Alves-Silva J., Ferrari C. Z., Izidoro-Toledo T. C., Silva J. F., Teixeira A. L., Souza D. G., Marques J. T., Teixeira M. M., Vieira L. B., and <\/span><span style=\"font-weight: 400;\"><u>Ribeiro F. M.<\/u><\/span><span style=\"font-weight: 400;\"> (2017) <\/span><span style=\"font-weight: 400;\">Zika virus promotes neuronal cell death in a non-cell autonomous manner by triggering the release of neurotoxic factors. <\/span><i><span style=\"font-weight: 400;\">Frontiers in Immunology<\/span><\/i><span style=\"font-weight: 400;\">, <\/span><b>8<\/b><span style=\"font-weight: 400;\">, 1016.<\/span><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3b1c70e e-con-full e-flex e-con e-child\" data-id=\"3b1c70e\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1bb36fd elementor-widget elementor-widget-button\" data-id=\"1bb36fd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/doi.org\/10.3389\/fimmu.2017.01016\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">PUBMED<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a872898 animated-slow e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"a872898\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;animation_delay&quot;:300}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-318ec04 e-con-full e-flex e-con e-child\" data-id=\"318ec04\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e6390cf elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"e6390cf\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li><span style=\"font-weight: 400;\">Silva F. R., Miranda A. S., Santos R. P. M., Olmo I. G., Zamponi G. W., Dobransky T., Cruz J. S., Vieira L. B., and <\/span><span style=\"font-weight: 400;\"><u>Ribeiro F. M.<\/u><\/span><span style=\"font-weight: 400;\"> (2017) N-type Ca<\/span><span style=\"font-weight: 400;\">2+<\/span><span style=\"font-weight: 400;\"> channels are affected by full-length mutant huntingtin expression in a mouse model of Huntington\u2019s disease. <\/span><i><span style=\"font-weight: 400;\">Neurobiology of Aging<\/span><\/i><span style=\"font-weight: 400;\">, <\/span><b>55<\/b><span style=\"font-weight: 400;\">, 1-10. <\/span><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3acad3d e-con-full e-flex e-con e-child\" data-id=\"3acad3d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ac4e82e elementor-widget elementor-widget-button\" data-id=\"ac4e82e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/doi.org\/10.1016\/j.neurobiolaging.2017.03.015\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">PUBMED<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-94c656d animated-slow e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"94c656d\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;animation_delay&quot;:300}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-ddf1b1e e-con-full e-flex e-con e-child\" data-id=\"ddf1b1e\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9f7fd3a elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"9f7fd3a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li><span style=\"font-weight: 400;\">Ferreira-Vieira T. H., Guimaraes I. M., Silva F. R., and <\/span><span style=\"font-weight: 400;\"><u>Ribeiro F. M.<\/u><\/span><span style=\"font-weight: 400;\"> (2016) Alzheimer&#8217;s disease: Targeting the cholinergic system. <\/span><i><span style=\"font-weight: 400;\">Current Neuropharmacology<\/span><\/i><span style=\"font-weight: 400;\">, <\/span><b>14<\/b><span style=\"font-weight: 400;\">, 101-115.<\/span><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-073b068 e-con-full e-flex e-con e-child\" data-id=\"073b068\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-304dad5 elementor-widget elementor-widget-button\" data-id=\"304dad5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/doi.org\/10.2174%2F1570159X13666150716165726\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">PUBMED<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0f5c6d9 animated-slow e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"0f5c6d9\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;animation_delay&quot;:300}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-540e284 e-con-full e-flex e-con e-child\" data-id=\"540e284\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5d25440 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"5d25440\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul>\n \t<li><a href=\"http:\/\/lattes.cnpq.br\/3010280132812544\"><span style=\"font-weight: 400; color: black\">Doria J. G.<\/span><\/a><span style=\"font-weight: 400;\">, de Souza J. M.,\u00a0<\/span><a href=\"http:\/\/lattes.cnpq.br\/7568012626967603\"><span style=\"font-weight: 400; color: black\">Andrade J. N.<\/span><\/a><span style=\"font-weight: 400;\">,\u00a0<\/span><a href=\"http:\/\/lattes.cnpq.br\/2622293530121592\"><span style=\"font-weight: 400; color: black\">Rodrigues H. A.<\/span><\/a><span style=\"font-weight: 400;\">, Guimaraes I. M., Carvalho T. G.,\u00a0<\/span><a href=\"http:\/\/lattes.cnpq.br\/2725844127749734\"><span style=\"font-weight: 400; color: black\">Guatimosim C.<\/span><\/a><span style=\"font-weight: 400;\">, Dobransky T., and <\/span><span style=\"font-weight: 400;\"><u>Ribeiro F. M.<\/u><\/span><span style=\"font-weight: 400;\"> (2015) The mGluR5 positive allosteric modulator, CDPPB, ameliorates pathology and phenotypic signs of a mouse model of Huntington&#8217;s disease. <\/span><i><span style=\"font-weight: 400;\">Neurobiology of Disease<\/span><\/i><span style=\"font-weight: 400;\">, <\/span><b>73<\/b><span style=\"font-weight: 400;\">, 163-173.<\/span><\/li>\n<\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-fad31de e-con-full e-flex e-con e-child\" data-id=\"fad31de\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-19433b7 elementor-widget elementor-widget-button\" data-id=\"19433b7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/doi.org\/10.1016\/j.nbd.2014.08.021\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">PUBMED<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-71cc6a5 animated-slow e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"71cc6a5\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;animation_delay&quot;:300}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-9333ebf e-con-full e-flex e-con e-child\" data-id=\"9333ebf\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-93667ce elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"93667ce\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul>\n \t<li><a href=\"http:\/\/lattes.cnpq.br\/8721252207572060\"><span style=\"font-weight: 400; color: black\"><u>Ribeiro F. M.<\/u><\/span><\/a><span style=\"font-weight: 400;\">, Devries R. A., Hamilton A., Guimaraes I. M., Cregan S. P.,\u00a0<\/span><a href=\"http:\/\/lattes.cnpq.br\/8356031036198869\"><span style=\"font-weight: 400; color: black\">Pires R. G. W.<\/span><\/a><span style=\"font-weight: 400;\">, and Ferguson S. S. G. (2013) Metabotropic glutamate receptor 5 knockout promotes motor and biochemical alterations in a mouse model of huntington&#8217;s disease. <\/span><i><span style=\"font-weight: 400;\">Human Molecular Genetics<\/span><\/i><span style=\"font-weight: 400;\">, <\/span><b>23<\/b><span style=\"font-weight: 400;\">, 2030-2042.<\/span><\/li>\n<\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f4284fe e-con-full e-flex e-con e-child\" data-id=\"f4284fe\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-99e079f elementor-widget elementor-widget-button\" data-id=\"99e079f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/doi.org\/10.1093\/hmg\/ddt598\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">PUBMED<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d3bc19f animated-slow e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"d3bc19f\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;animation_delay&quot;:300}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-bd22512 e-con-full e-flex e-con e-child\" data-id=\"bd22512\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-fc14cb2 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"fc14cb2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li><span style=\"font-weight: 400;\">Doria J. G., Silva F. R., Souza J. M., Vieira L. B., Carvalho T. G., Reis H. J., Pereira G. S. Dobransky T., and <\/span><span style=\"font-weight: 400;\"><u>Ribeiro F. M.<\/u><\/span><span style=\"font-weight: 400;\"> (2013) Metabotropic glutamate receptor 5 positive allosteric modulators are neuroprotective in a mouse model of Huntington\u2019s disease. <\/span><i><span style=\"font-weight: 400;\">British Journal of Pharm.<\/span><\/i><span style=\"font-weight: 400;\">, <\/span><b>169<\/b><span style=\"font-weight: 400;\">, 909-921.<\/span><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-66ccca4 e-con-full e-flex e-con e-child\" data-id=\"66ccca4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e7e516f elementor-widget elementor-widget-button\" data-id=\"e7e516f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/doi.org\/10.1111\/bph.12164\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">PUBMED<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-244ba3e animated-slow e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"244ba3e\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;,&quot;animation_delay&quot;:300}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-78268ac e-con-full e-flex e-con e-child\" data-id=\"78268ac\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-eb9b396 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"eb9b396\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul>\n<li><span style=\"font-weight: 400;\"><u>Ribeiro F. M.<\/u><\/span><span style=\"font-weight: 400;\">, Paquet M., Ferreira L. T., Cregan T., Cregan S., and Ferguson S. S. G. (2010) Metabotropic glutamate receptor-mediated cell signaling pathways are altered in a mouse model of Huntington\u2019s disease. <\/span><i><span style=\"font-weight: 400;\">J. Neuroscience, <\/span><\/i><b>30<\/b><span style=\"font-weight: 400;\">, 316-24.<\/span><\/li>\n<\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2605216 e-con-full e-flex e-con e-child\" data-id=\"2605216\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-59eb0f2 elementor-widget elementor-widget-button\" data-id=\"59eb0f2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/doi.org\/10.1523\/JNEUROSCI.4974-09.2010\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">PUBMED<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7f0fa8a e-flex e-con-boxed e-con e-parent\" data-id=\"7f0fa8a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4e8efe6 elementor-widget elementor-widget-spacer\" data-id=\"4e8efe6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Principais Publica\u00e7\u00f5es de Souza J. M., Ferreira-Vieira T. H., Maciel E. M. A., Silva N. C., Lima I. B. Q., Doria J. G., Olmo I. G., Ribeiro F. M. (2022) mGluR5 ablation leads to age-related synaptic plasticity impairments and does not improve Huntington&#8217;s disease phenotype. Scientific Reports, 12, 8982. PUBMED Andrade T. A., Fahel J. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-458","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Publica\u00e7\u00f5es - Laborat\u00f3rio Neurobioqu\u00edmica - Universidade Federal de Minas Gerais<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.icb.ufmg.br\/neurobioquimica\/publicacoes\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publica\u00e7\u00f5es - Laborat\u00f3rio Neurobioqu\u00edmica - Universidade Federal de Minas Gerais\" \/>\n<meta property=\"og:description\" content=\"Principais Publica\u00e7\u00f5es de Souza J. M., Ferreira-Vieira T. H., Maciel E. M. A., Silva N. C., Lima I. B. Q., Doria J. G., Olmo I. G., Ribeiro F. M. (2022) mGluR5 ablation leads to age-related synaptic plasticity impairments and does not improve Huntington&#8217;s disease phenotype. Scientific Reports, 12, 8982. PUBMED Andrade T. A., Fahel J. 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