{"id":501,"date":"2023-11-03T16:33:47","date_gmt":"2023-11-03T19:33:47","guid":{"rendered":"https:\/\/neurobioquimica-com.umbler.net\/?p=501"},"modified":"2024-03-25T15:36:56","modified_gmt":"2024-03-25T18:36:56","slug":"3-fatos-sobre-a-esquizofrenia","status":"publish","type":"post","link":"https:\/\/sites.icb.ufmg.br\/neurobioquimica\/3-fatos-sobre-a-esquizofrenia\/","title":{"rendered":"3 fatos sobre a esquizofrenia"},"content":{"rendered":"\t\t
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3 fatos sobre a esquizofrenia: um dos focos de pesquisa do nosso laborat\u00f3rio<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Fato 1: Aproximadamente 1,6 milh\u00e3o de brasileiros t\u00eam esquizofrenia<\/span><\/p>

De acordo com a Organiza\u00e7\u00e3o Mundial da Sa\u00fade (OMS), o n\u00famero de pessoas com transtornos mentais em todo o mundo est\u00e1 aumentando, principalmente em pa\u00edses de baixa renda<\/span>. Al\u00e9m disso, S\u00e3o Paulo est\u00e1 entre as cidades com maior preval\u00eancia de indiv\u00edduos que sofrem com transtornos mentais<\/span>. S\u00f3 no Brasil, a esquizofrenia afeta cerca de 1,6 milh\u00e3o de pessoas<\/span>. Atualmente, esses pacientes contam com o apoio do Sistema \u00danico de Sa\u00fade (SUS), que oferece servi\u00e7os de assist\u00eancia social, psicol\u00f3gica e reabilita\u00e7\u00e3o, al\u00e9m de rem\u00e9dios antipsic\u00f3ticos que s\u00e3o importantes para o controle da doen\u00e7a.<\/span><\/p>

Fato 2: A doen\u00e7a afeta homens e mulheres de maneira diferente<\/span><\/p>

A incid\u00eancia de esquizofrenia \u00e9 geralmente maior em homens do que em mulheres<\/span>, mas as diferen\u00e7as observadas entre indiv\u00edduos do sexo masculino e feminino na esquizofrenia n\u00e3o acabam por ai. A literatura aponta que a idade de in\u00edcio da doen\u00e7a \u00e9 maior entre as mulheres. Estudos relatam, em homens, pico de in\u00edcio entre as idades de 15 e 25 anos, enquanto em mulheres, observa-se um pico entre 20 e 35 anos, com um segundo pico menor, entre 45 e 49 anos de idade<\/span>. N\u00edveis reduzidos de estrog\u00eanio ap\u00f3s a menopausa t\u00eam sido propostos como uma explica\u00e7\u00e3o para o aumento da preval\u00eancia em mulheres com mais de 40 anos de idade<\/span>.<\/span><\/p>

Fato 3: A urbanicidade \u00e9 um dos fatores de risco da esquizofrenia<\/span><\/p>

A esquizofrenia \u00e9 considerada um dist\u00farbio multifatorial. Dessa forma, sabe-se que fatores gen\u00e9ticos e estressores ambientais precisam atuar juntos para promover altera\u00e7\u00f5es nos padr\u00f5es do neurodesenvolvimento, e assim desencadear o dist\u00farbio<\/span>. Dentre esses estressores ambientais, \u00e9 poss\u00edvel citar a urbanicidade. Crescer ou viver em um ambiente urbano tem sido frequentemente associado a um risco aumentado de desenvolver esquizofrenia<\/span>. Um estudo interessante realizado na Dinamarca mostrou haver associa\u00e7\u00e3o entre viver em locais com quantidade de espa\u00e7o verde reduzida e o maior risco de desenvolver esquizofrenia. Esse estudo indicou, portanto, que a proximidade a \u00e1reas verdes \u00e9 um fator protetor contra a doen\u00e7a<\/span>.<\/span><\/p>

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Refer\u00eancias:<\/b><\/p>

1 WORLD HEALTH ORGANIZATION. Depression and Other Common Mental Disorders: Global Health Estimates. Geneva: World Health Organization; 2017.<\/span><\/p>

2 ANDRADE,LH. <\/span>et al<\/span>. Mental Disorders in Megacities: Findings from the S\u00e3o Paulo Megacity Mental Health Survey, Brazil. PLoS ONE, v. 7, n. 2, 2012. Dispon\u00edvel em: <https:\/\/doi.org\/10.1371\/journal.pone.0031879>.<\/span><\/p>

3 MATOS, G. <\/span>et al<\/span>. Esquizofrenia, a desordem esquecida: o cen\u00e1rio no Brasil. Revista Brasileira de Psiquiatria, v. 37, n. 4, p. 269-270, 2015. Dispon\u00edvel em: <https:\/\/doi.org\/10.1590\/1516-4446-2015-1827>.<\/span><\/p>

4 SOMMER, I.E., <\/span>et al<\/span>. The clinical course of schizophrenia in women and men\u2014a nation-wide cohort study. npj Schizophr, v. 6, n. 12, 2020. Dispon\u00edvel em: <https:\/\/doi.org\/10.1038\/s41537-020-0102-z>.<\/span><\/p>

5 H\u00c4FNER, H., MAURER, K., L\u00d6FFLER, W., & RIECHER-R\u00d6SSLER, A. The Influence of Age and Sex on the Onset and Early Course of Schizophrenia. British Journal of Psychiatry, v. 162, n.1, p. 80-86, 1993. doi:10.1192\/bjp.162.1.80<\/span><\/p>

6 MARKHAM, J.A. Sex steroids and schizophrenia. Rev Endocr Metab Disord, v. 13, p. 187\u2013207, 2012. Dispon\u00edvel em: <https:\/\/doi.org\/10.1007\/s11154-011-9184-2>.<\/span><\/p>

7 MULLER, N. <\/span>et al<\/span>. The role of inflammation in schizophrenia. Front Neurosci, v. 9, p. 372, 2015. Dispon\u00edvel em: < https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26539073 >.<\/span><\/p>

8 NIMGAONKAR, V. L. <\/span>et al<\/span>. The complement system: a gateway to gene-environment interactions in schizophrenia pathogenesis. Mol Psychiatry, v. 22, n. 11, p. 1554-1561, Nov 2017. Dispon\u00edvel em: <https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28761078 >.<\/span><\/p>

9 VAN OS, J. <\/span>et al<\/span>. Prevalence of psychotic disorder and community level of psychotic symptoms: an urban-rural comparison. Archives of general psychiatry, v. 58, n. 7, p. 663-668, 2001. Dispon\u00edvel em: <doi:10.1001\/archpsyc.58.7.663>.<\/span><\/p>

10 KRABBENDAM, L.; VAN OS, J. Schizophrenia and urbanicity: a major environmental influence\u2014conditional on genetic risk. Schizophrenia bulletin, v. 31, n. 4, p. 795-799, 2005. Dispon\u00edvel em: <https:\/\/doi.org\/10.1093\/schbul\/sbi060>.<\/span><\/p>

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11 ENGEMANN, K. <\/span>et al<\/span>. Childhood exposure to green space\u2013a novel risk-decreasing mechanism for schizophrenia?. Schizophrenia research, v. 199, p. 142-148, 2018. Dispon\u00edvel em: <<\/span>https:\/\/doi.org\/10.1016\/j.schres.2018.03.026<\/span><\/a>>.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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3 fatos sobre a esquizofrenia: um dos focos de pesquisa do nosso laborat\u00f3rio Fato 1: Aproximadamente 1,6 milh\u00e3o de brasileiros t\u00eam esquizofrenia De acordo com a Organiza\u00e7\u00e3o Mundial da Sa\u00fade (OMS), o n\u00famero de pessoas com transtornos mentais em todo o mundo est\u00e1 aumentando, principalmente em pa\u00edses de baixa renda. Al\u00e9m disso, S\u00e3o Paulo est\u00e1 […]<\/p>\n","protected":false},"author":1,"featured_media":525,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-501","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sem-categoria"],"yoast_head":"\n3 fatos sobre a esquizofrenia - Laborat\u00f3rio Neurobioqu\u00edmica - Universidade Federal de Minas Gerais<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.icb.ufmg.br\/neurobioquimica\/3-fatos-sobre-a-esquizofrenia\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"3 fatos sobre a esquizofrenia - Laborat\u00f3rio Neurobioqu\u00edmica - Universidade Federal de Minas Gerais\" \/>\n<meta property=\"og:description\" content=\"3 fatos sobre a esquizofrenia: um dos focos de pesquisa do nosso laborat\u00f3rio Fato 1: Aproximadamente 1,6 milh\u00e3o de brasileiros t\u00eam esquizofrenia De acordo com a Organiza\u00e7\u00e3o Mundial da Sa\u00fade (OMS), o n\u00famero de pessoas com transtornos mentais em todo o mundo est\u00e1 aumentando, principalmente em pa\u00edses de baixa renda. 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