Guatimosim's Lab
The Guatimosim lab is an interdisciplinary group interested in the molecular and cellular mechanisms that lead to cardiac disfunction, aiming to provide novel therapeutic insights. We use modern techniques and a variety of genetically modified animal models in order to investigate signalling pathways that mediate calcium dynamics and cardiomyocyte contractility.
Contractionwave Software
CONTRACTIONWAVE (CW) is a free software developed in Python Programming Language that allows the user to visualize, quantify, and analyze cell contractility parameters in a simple and intuitive format. The software enables the user to acquire membrane kinetics data of cell contractility during contraction-relaxation cycles through image capture and a dense optical flow algorithm.